| Sunrise Course:
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| Potentials & Challenges
of High-Field MRS |
| Organizers: Rolf Gruetter, Ph.D.,
and Ivan Tkac,
Ph.D. |
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| Skill Level:
Intermediate |
| Tuesday - Friday, 4-7 May
2010 |
| 07:00 - 08:00 |
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OVERVIEW |
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This four-hour course will focus on main
methodological areas problematic for advanced MRS at high magnetic
fields. Our first goal will be to demonstrate potentials of MRS for
neuroscience research and clinical diagnostics. Second, is to
describe all major challenges of MRS at very high fields and to
explain possible solutions for an efficient shimming, for a design
of pulse sequence and appropriate processing tool for metabolite
quantification. Finally, yet importantly, the strengths of MRS
techniques at ultra-high fields will be demonstrated on applications
using animal models. |
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EDUCATIONAL OBJECTIVES |
Upon completion of this course
participants should be able to:
- Describe advantages and
potentials of MRS at very high fields;
- Identify problems and challenges
of high field MRS;
- Define the MRS detectable
neurochemical profile of the brain;
- Describe principles of
metabolite quantification;
- Assess spectral quality and
identify main sources of spectral quality deterioration; and
- Explain the importance of B0
shimming at high fields.
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