| Weekend Educational Course:
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| Preclinical MR of Cancer |
| Organizers:
Carles Arús, Ph.D., and Sabrina M. Ronen, Ph.D. |
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| Skill Level:
Basic - Intermediate |
| Saturday, 1 May
2010 |
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OVERVIEW |
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This one-day course focuses on cancer in
preclinical models and integrates MR imaging, MR spectroscopy and MR
spectroscopic imaging studies. It is designed for research
scientists and physicians (radiologists and oncologists) who wish to
be updated on the current state of the art in MR techniques for the
investigation of preclinical models. Accordingly, most of the
speakers will be PhDs. The first part of the course will be geared
to beginners, and will describe the basic ‘how to’ aspects of a
range of preclinical methods in different types of models. The
second part of the course will be geared to beginners/intermediates,
and will cover the application of the methods outlined in part one
to preclinical cancer research. It will cover well-established
applications and emerging state-of-the-art approaches. Thus it is
hoped that the second part of the course will also prepare
participants for new cancer-related MR applications that may emerge
in the next few years. |
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EDUCATIONAL OBJECTIVES |
Upon completion of this course
participants should be able to:
- Recognize the basic MRI, MRS and
MRSI technologies which should be available in state-of-the art
spectrometers for preclinical cancer research studies, including
studies of cells, tissue samples and animal models;
- Identify potential pitfalls and
methodological requirements for carrying adequate preclinical MR
studies of cancer;
- List recognized biomarkers of
cancer accessible from preclinical MR studies of cancer models;
- Describe the principal
applications of basic MRI, MRS and MRSI technologies in
preclinical cancer research studies;
- Select MRI, MRS and MRSI
biomarkers of cancer to use for modeling diagnosis, therapy
planning and therapeutic outcome assessment; and
- Recognize the added value of
multiparametric biomarker analysis in preclinical MR of cancer.
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| 08:30 |
How to Study in Cancer Cell
Models |
E. Jim Delikatny,
Ph.D. |
| 09:00 |
How to Perform HR-MAS
Studies in Tissue |
Ingrid S.
Gribbestad, Ph.D. |
| 09:30 |
How to Do MRS/MRSI in Animal
Models |
Arend Heerschap,
Ph.D. |
| 10:00 |
Break
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10:00 - 10:15 Meet the
Teachers
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| 10:30 |
How to Perform MRI in Animal
Models |
Chantal Rémy,
Ph.D. |
| 11:00 |
Obtaining & Presenting
Multi-Parametric Biomarker Data |
John Kurhanewicz,
Ph.D. |
| 11:30 |
Choline in Cancer
|
Kristine Glunde,
Ph.D. |
| 12:00 |
Break |
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12:00 - 12:15 - Meet the
Teachers |
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| 13:30 |
Neutral Lipids in Cancer
|
Juhana M.
Hakumäki, M.D. |
| 14:00 |
Energy Metabolism in Cancer
- not available |
Carles Arús,
Ph.D. |
| 14:30 |
pH in Cancer
|
Sebastián Cerdán,
Ph.D. |
| 15:00 |
Break |
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15:00 - 15:15 Meet the
Teachers
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| 15:30 |
Vasculature in Cancer
|
Hagit Dafni,
Ph.D. |
| 16:00 |
Diffusion in Cancer |
Thomas L.
Chenevert, Ph.D. |
| 16:30 |
Drug Delivery & Response
in Cancer |
Yuen-Li Chung,
Ph.D. |
| 17:00 |
Adjournment |
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17:00 - 17:15 - Meet the
Teachers |
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