ISMRM21 - Diffusion-Weighted Imaging of the Breast: State of the Art & Beyond

Diffusion-Weighted Imaging of the Breast: State of the Art & Beyond

Member-Initiated Symposium

Tuesday, 18 May 2021

Concurrent 7

15:00 - 15:30

Moderators: Mami Iima & Denis Le Bihan

Session Number: MIS-02

Parent Session: Diffusion-Weighted Imaging of the Breast: State of the Art & Beyond

Session Number:MIS-02

Organizers
Mami Iima, Denis Le Bihan, Katja Pinker-Domenig

Overview
DWI is increasingly incorporated into breast MRI protocols worldwide. Its prime focus is differentiation between benign and malignant lesions in the breast, aiming to prevent unnecessary breast biopsies. To improve consistency and reproducibility between sites, the EUSOBI International Breast Diffusion-Weighted Imaging working group recently published a consensus and mission statement that forms the starting point of this symposium. It identifies quality control as a key requirement for successful integration of DWI, which is the focus of the second lecture of this symposium. Subsequent lectures discuss indications in breast imaging in which DWI may play a pivotal role in the near future. For one, DWI may offer a highly sensitive method to detect early breast cancer without the costs and safety concerns associated with contrast-enhanced alternatives. DWI also appears to be a strong prognostic biomarker for breast cancer and may be used for prediction of treatment response and thus selection of the most appropriate therapy. The last lectures of this symposium focus on DWI beyond the state of the art. Advanced DWI models such as intravoxel incoherent motion (IVIM) and diffusion tensor imaging (DTI) are making their way into clinical breast imaging. This is further enhanced by adjusting acquisition parameters and implementing advanced analysis tools, yielding even better insight in tissue biology.

Target Audience
Radiologists and scientists interested in breast DWI: its current state-of-art, technical advances and emerging clinical indications.

Educational Objectives
As a result of attending this course, participants should be able to:
Upon completion of this course, participants should be able to: - Describe the current standards for breast DWI and explain why standardization is important; - Explain the need for quality control and identify methods to optimize breast diffusion acquisition; - Describe the upcoming clinical applications of diffusion-weighted imaging in breast cancer for screening and therapy; and - Evaluate the potential of technical advances in diffusion-based imaging of the breast, including DTI, IVIM, RSI etc., and defend their clinical value.

			DWI of the Breast: Concepts for Clinical Practice Ritse Mann Department of radiology and nuclear medicine, Radboud University Medical Centre, Nijmegen, and Depar
			DWI of the Breast: Technical Optimization & QC Savannah Partridge Department of Radiology, University of Washington, Seattle, Washington, USA
			DWI-Based Screening for Breast Cancer Taro Takahara Department of Biomedical Engineering, Tokai University School of Engineering, Kanagawa, Japan
			DWI of the Breast: Clinical Implementation Katja Pinker-Domenig Department of Radiology, Breast Imaging Service, Memorial Sloan Kettering Cancer Center, NY, New Yor
			Translational Advanced DWI of the Breast Mami Iima Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine,
			Frontiers of Advanced DWI of the Breast Eric Sigmund Department of Radiology, NYU Langone Health, New York, New York, USA