ISMRM21 - Frontiers & Challenges in Small Animals Resting-State Functional MRI

Frontiers & Challenges in Small Animals Resting-State Functional MRI

Member-Initiated Symposium

Monday, 17 May 2021

Concurrent 8

18:00 - 20:00

Moderators: Joanes Grandjean

Session Number: MIS-11

Parent Session: Frontiers & Challenges in Small-Animal Resting-State Functional MRI

Session Number:MIS-11

Organizers
Marc Dhenain

Overview
Preclinical applications of resting-state functional magnetic resonance imaging (rsfMRI) offers the possibility to non-invasively probe whole-brain network dynamics and to investigate the determinants of altered network signatures observed in human studies. Mouse and small-primate rsfMRI have been increasingly adopted by numerous laboratories worldwide. Frontiers in small animal-resting-state imaging include development of optimized methods for data acquisition and analysis, development of novel methods to couple rsfMRI with protocols able to modulate neuronal networks to assess mechanisms modifying neuronal networks. Characterizing resting-state networks evolution in different species is also critical to evaluate the translational value of animal models for human pathologies. Finally, the impact of cerebral diseases on networks impairments and how therapies can modulate networks is still very challenging. Each speaker in this session will address one or more of the challenges and present new data at the frontier of the field of rodent and primate resting-state fMRI.

Target Audience
Clinicians; researchers investigating brain function and brain disorders; trainees learning how to apply and interpret resting-state fMRI.

Educational Objectives
As a result of attending this course, participants should be able to:
Upon completion of this course, participants should be able to: - Identify techniques to study cerebral networks in rodent and primates; - Explain resting-state network evolution in different species; and - Describe new findings obtained through resting-state MR imaging of rodent/primate brains that inform human conditions.

			Multicentre Resting-State fMRI Analysis: Towards Recommendation for Optimized Image Acquisition & Analysis Francesca Mandino The University of Manchester
			Resting-State Cerebral Networks Across Species: An Evolutionary Perspective Clément Garin Wake Forest School of Medicine
			Impairments of Cerebral Networks in Animal Models of Psychiatry Joanes Grandjean Radboud University Medical Center
			A Novel Oscillatory Activity of the Thalamic Reticular Nucleus & Its Relation to Resting-State Networks of the Brain Norio Takata Keio University School of Medicine
			Multimodal Approach to Image Cortical Calcium Activity Concurrently with fMRI: New Tools to Understand the Impact of Neuronal Activity on Resting-State Organization Evelyn Lake Yale School of Medicine