ISMRM21 - Preclinical MRI: Small Is Beautiful: Opportunities & Challenges at Ultra-High Field

Preclinical MRI: Small Is Beautiful: Opportunities & Challenges at Ultra-High Field

Sunrise Session

ORGANIZERS: Alan Koretsky, Christoffer Laustsen, Harish Poptani

Monday, 17 May 2021

Concurrent 7

16:00 - 17:00

Moderators:

Skill Level: Basic to Intermediate

Session Number: S-01a

Parent Session: Preclinical MRI

Session Number: S-01a

Overview
Pre-clinical has been instrumental in development of advanced MR methods and in understanding basic biology. The goal of this session is to give the attendees an overview of the cutting-edge science using ultra-high field pre-clinical MR systems. Emphasis is on the latest results using the highest fields available for small-animal imaging.

Target Audience
The session is aimed at a wider audience and is not organ- or disease-specific and should be of interest to students/physicians and researchers interested in preclinical applications.

Educational Objectives
As a result of attending this course, participants should be able to:
- Recognize the value of ultra-high field pre-clinical MR for small animal imaging;
- Recognize the limitations of ultra-high field pre-clinical MR; and
- Recognize the benefits of both vertical and horizontal MR.

		Horizontal Ultra-High Field Preclinical MRI Watch the Video Luisa Ciobanu The intent of this presentation is to provide a basic overview of preclinical MRI at ultra-high magnetic field. In conjunction with the high field magnet, other hardware components such as gradient coils and radiofrequency detectors are critical in obtaining the sensitivity and spatial resolutions needed to image small animals. The enhanced magnetic susceptibility contrast enables high-resolution functional MRI studies allowing the characterization of neuronal activity in specific brain structures and makes possible the direct comparison with non-MR microscopic techniques. Besides functional MRI, UHF is particularly advantageous for applications such as chemical exchange saturation transfer, spectroscopy imaging and non-proton imaging.
		Vertical Ultra-High Field Preclinical MRI Samuel Grant