ISMRM21 - IVIM in the Brain

IVIM in the Brain

Sunrise Session

ORGANIZERS: Rajan Jain, Marta Bianciardi

Wednesday, 19 May 2021

Concurrent 7

14:00 - 15:00

Moderators: Eyal Lotan

Skill Level: Basic to Advanced

Session Number: S-04d

Parent Session: Hot Topics in MRI of the Brain

Session Number: S-04d

Overview
IVIM methodology and its role in clinical neuro-imaging will be discussed.

Target Audience
Clinical radiologists, data scientists, physicists, and neuro-scientists.

Educational Objectives
As a result of attending this course, participants should be able to:
- Explain IVIM methodology and physics;
- List clinical applications of IVIM in brain tumors; and
- Recall clinical applications of IVIM in stroke, cerebrovascular reserve and beyond.

		IVIM: Brain Tumor Applications Watch the Video Ho Sung Kim Intravoxel incoherent motion (IVIM) magnetic resonance imaging technique aims to separate water molecule diffusion (D) component and microvascular perfusion or pseudo‐diffusion (D) component in the diffusion‐weighted (DW) signals of tissues. Perfusion‐related information (pseudo‐diffusion D, perfusion fraction F) was shown to be able to diagnose brain tumors. Because D values is not reliant on the effects of perfusion, the state of diffusion can be more accurately depicted than through conventional ADC measurements. IVIM does not require the use of intravenous contrast agents and can, therefore, be administered to children, pregnant women, patients with a previous anaphylactic reaction to gadolinium-based contrast agents.
		IVIM: Stroke & Beyond Watch the Video Christian Federau The property of the IVIM perfusion method to be essentially local, in the sense that both excitation and read-out are done in the same plane, is particularly interesting for local blood flow measurement in cases of slow and dispersive arterial inflowing blood flow, as might be the case in hyperacute cerebral stroke or for example in severe chronic stenosis, such as of the carotid artery.