JULY 2013 • Vol. 2, Issue 3


Milestone 60th Home Study: Diffusion Weighted Imaging in the Breast

Anne Marie Sawyer, B.S., R.T.(R)(MR), FSMRT
Editor

"Diffusion-weighted MR imaging that can be used to measure apparent diffusion coefficients (ADCs) - a quantitative measure of the diffusivity of water - provides information related to tumor cellularity and the integrity of cell membranes and is sensitive to intratumoral changes induced by chemotherapy."

We are pleased to present the SMRT Educational Seminars, Volume 16, Number 2: “Diffusion-Weighted MR Imaging of the Breast.” This is the 60th accredited home study developed by the SMRT, exclusively for SMRT members. The accreditation is conducted by the SMRT acting as a RCEEM (Recognized Continuing Education Evaluation Mechanism) for the ARRT. Category A credits are assigned to each home study, which can be used to maintain one’s ARRT advanced registry. SMRT Home Studies are also approved for AIR (Australian Institute of Radiography), NZIMRT (New Zealand Institute of Radiation Technology) and CPD Now (The College of Radiographers, United Kingdom) continuing professional development (CPD) activities.

Three peer-reviewed articles have been chosen for this home study issue. The authors of the first, "Diffusion-Weighted MR Imaging: Pretreatment Prediction of Response to Neoadjuvent Chemotherapy in Patients with Breast Cancer," introduce their article by saying "Diffusion-weighted MR imaging that can be used to measure apparent diffusion coefficients (ADCs) - a quantitative measure of the diffusivity of water - provides information related to tumor cellularity and the integrity of cell membranes and is sensitive to intratumoral changes induced by chemotherapy." Because previous " . . . clinical studies performed in patients with breast cancer have shown that changes in ADCs precede changes in tumor diameter. However, different chemotherapeutic regimens were used, which may affect the treatment response." Their purpose in conducting the study was to focus on a single chemotherapeutic regimen, specific changes in ADC values, and continue the investigation.

In the second article, "Differential Diagnosis of Mammographically and Clinically Occult Breast Lesions on Diffusion-Weighted MRI", the authors investigate the role of DWI as an alternative to DCE-MRI in the screening of breast cancer. They state " . . . the requirement for intravenous administration of a gadolinium-based contrast agent increases the associated time, costs, and potential toxicity of the breast DCE-MRI examination. These factors limit the accessibility of this screening tool for many women."

The third and final article, "Diffusion-Weighted MRI as an Adjunct to Mammography in Women Under 50 years of Age: An Initial Study", seeks to " . . . evaluate whether DW imaging can supplement mammography, particularly for the detection of small invasive breast cancer in women under 50 years of age." They acknowledge that previous studies have been conducted that "have already shown the value of this method (DW MRI) in the characterization of breast mass lesions. However, only one blinded study has examined DW imaging for detection of breast cancer."

A special thank you to Nancy Hill Beluk from the Pediatric Imaging Research Center, Children’s Hospital of Pittsburgh (UPMC), Pennsylvania, USA for acting as the Expert Reviewer.

Thanks also to Heidi Berns, M.S., R.T.(R)(MR), FSMRT, Chair of the SMRT RCEEM Ad-hoc Committee from Coralville, Iowa, USA and all those who participate on this committee by reviewing the home studies for accreditation. Finally, thanks to Jennifer Olson, Associate Executive Director, Mary Keydash, Publications Director, Linda O-Brown, SMRT Coordinator, and the entire staff in the Berkeley, California, USA office of the ISMRM and SMRT for their insight and long hours spent supporting these educations symposia.

We would also like to thank John Wilkie and all of the individuals at Invivo Corporation (Philips Healthcare) who generously support our home studies program. Their continuing investment advances technologist and radiographer knowledge and brings quality continuing education to the SMRT membership worldwide.